Deca Durabolin – Reducing Oxidative Stress in a Non-Drug Treatment For Diabetes
Deca Durabolin is a prescription diet pill made from an herb called Epimedium. It is available by prescription only. It has been approved for weight loss in women and preliminary studies suggest it might have some benefit for men with enlarged prostate. Epimedium is a plant commonly found in China, Pakistan, Tibet, Nepal, India and the United States. Nandrolone is an androgenic androgen which means it affects male hormones. Nandrolone, like all anabolic steroids is subject to the possible side effects of long term use.
Deca Durabolin (common name for it is Deca EDTA) is a dietary supplement that was developed by Novartis Pharmaceuticals for the treatment of patients with obese, insulin-resistant conditions. It is similar to many other diet supplements, but not as prevalent in commercial mass building products. The fact that it was initially designed for the obese and insulin resistant raises questions about how effective it would be if it were actually marketed for weight loss. A study was conducted by the Journal of Toxicology and Environmental Health to test the effects on mice and rats. The conclusion was that the product caused death in all three tests except in the most extreme case where it caused death in one out of five mice, which was deemed to be a non-issue.
Anabolic steroids such as nandrolone (including Deca Durabolin), are androgens. They work by increasing the rate of cell division in our bodies. The growth hormone that naturally occurs in our bodies is converted into nandrolone by the liver. There is a reason why steroids are illegal; they are androgenic in nature. Anabolic steroids such as nandrolone can cause an increase in the size of cells without them being able to grow independently of the uterus and fallopian tubes.
Deca Durabolin is not anabolic steroids. Instead, it is a dietary supplement that is intended to support weight loss. As mentioned above, the product contains an ingredient called nandrolone, which is also part of the family of steroids. Although nandrolone is not technically steroids, they are still considered to be anabolic steroids by the FDA. As a result, any use of Deca Durabolin, even under medical supervision, could potentially be considered as use of anabolic steroids.
Anabolic-androgenic steroids, including Deca Durabolin, work by stimulating the body’s production of testosterone and nongenital steroids. The action of these hormones depends on the action of certain enzymes on the retinoids and luteinizing enzymes (LH, LH hormone). Enzymes produce androgenic hormones by binding to the androgen receptors on the target cells. When certain hormones stimulate the target cell’s production of growth hormone (GH), other hormones stimulate the opposite action. This is how anabolic-androgenic steroids work.
Anabolic steroids such as Deca Durabolin inhibit the action of the enzyme aromatase, which causes the conversion of testosterone to estrogen (in women). However, contrary to popular belief, the metabolism of testosterone (in both men and women) does not stop when it reaches the target cell. Instead, the target cell undergoes a rapid phase of autocrine hyperplasia, resulting in a large number of immature mature target cells (granulocytes random) and a massive surge in the flux of free radicals into the cell. As a result, the body ends up using up more of its antioxidant enzymes to deal with the damage caused by the excess free radicals. The result is that as the liver detoxifies the excess free radicals, more damage is repaired through the action of the antioxidants.
The active ingredient in Deca Durabolin is a carboxylic acid known as “carbinol”, which is unique among ingredients because it has no known function in fighting free radical damage in the liver. Instead, carbinol acts as an enabler for the synthesis of another type of antioxidant, Thioctic acid. Thioctic acid has been shown in animal studies to counter the oxidative stress caused by high carbohydrate diets (which are common in western diets). Whether or not the same effects can be achieved in human liver is not currently known.
In addition to helping to repair liver damage, Deca Durabolin appears to help relieve other symptoms of diabetes, particularly by protecting the kidneys from the onset of chronic kidney disease (CKD). Some preliminary studies appear to indicate that Deca Durabolin may also be effective at reducing symptoms of asthma, arthritis and other inflammatory diseases. All of these benefits, however, must be compared with the relatively low oral dose of this herbal supplement, which may not produce the same beneficial effect in the bloodstream. Current clinical trials are underway, however, and the results will likely be supportive of the claim that Deca Durabolin helps to reduce oxidative stress. If further research indicates that the herbal supplement is at least as effective at combating oxidative stress as prescription anti-oxidants, it may become one of the more potent drugs against chronic disease. No treatment currently exists that will rid the body of all free radicals, but herbal supplements such as Deca Durabolin could pave the way toward a world without serious chronic illness.